ICT is pleased to announce the upcoming release of a far-red fluorescence-emitting inhibitor probe for the in vitro detection of activated caspase-1 (ICE) enzyme.
FLICA™ 660 Caspase-1 Detection Reagent, 660-YVAD-FMK, allows for the rapid...
Caspase Detection
Feb 17, 2012
Dissemination of invasive Salmonella via bacterial-induced extrusion of mucosal epithelia
Leigh A. Knodler, Bruce A. Vallance, Jean Celli, Seth Winfree, Bryan Hansen, Marinieve Montero, and Olivia Steele-Mortimer
PNAS. 2010; 107:17733-17738. [...
Oct 17, 2011
Magic Red™ Caspase-3/7 detection assays measure apoptosis-associated DEVDase enzyme activity in living, intact cells.
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Sep 20, 2011
Caspase-1 (ICE)
• Originally identified as Interleukin -1β Converting Enzyme or ICE
• Cleaves IL-1 beta and IL-18 into active forms
• Creation of the inflammasome during host responses to pathogens leads to the activation of caspase-1
• Active caspase-1...
Aug 23, 2011
Apoptosis is an evolutionarily conserved form of cell suicide responsible for various biological processes including the normal turnover of cells and the proper functioning of the immune system. This process of...
Aug 23, 2011
Apoptosis is an evolutionarily conserved form of cell suicide responsible for various biological processes including the normal turnover of cells and the proper functioning of the immune system. This process of...