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NEW: Near-Infrared Tracers for Non-Invasive In Vivo Imaging of Apoptosis

Tumors within living mouse models show high apoptosis levels with NIR-FLIVO 747 after receiving an experimental treatment to induce cell death. Near-infrared FLIVO tracers are available with 690/709 and 747/776 excitation/emission pairings.

ICT is pleased to announce the launch of two near-infrared labeled FLIVO™ tracers for non-invasive in vivo optical imaging of apoptosis. NIR-FLIVO™ 690 and NIR-FLIVO™ 747 in vivo apoptosis kits and free dye control kits are now available from ImmunoChemistry Technologies at introductory pricing.

NIR-FLIVO™ 690 in vivo Apoptosis Tracer and Kit  #6306, #9112
NIR-FLIVO™ 690 Free Dye Control Reagent and Kit  #6307, #9113
NIR-FLIVO™ 747 in vivo Apoptosis Tracer and Kit  #6308, #9114
NIR-FLIVO™ 747 Free Dye Control Reagent and Kit  #6309, #9115

FLIVO™, our proprietary in vivo apoptosis tracer, is a non-toxic, cell-permeant reagent that specifically labels apoptotic cells in vivo for analysis with fluorescence detection methods. This tracer, or fluorescent probe, has been successfully used in a range of animal models to assess apoptosis as a result of a treatment or biological condition.

The new NIR-FLIVO™ apoptosis tracers utilize the near-infrared fluorescent labels DyLight® 690 and DyLight® 747 for noninvasive detection with whole animal imaging systems. Additional FLIVO™ tracers are available with carboxyfluorescein (FAM, green) or sulforhodamine-B (SR, red) labels for ex vivo optical imaging or flow cytometric analysis of histological samples. These first-generation FLIVO tracers have proven to be useful for in vivo labeling of apoptotic cells, such as detecting apoptosis in vivo in ischemic hepatic tissue and in vivo labeling of cutaneous or shallow subcutaneous tumor growth entities.  These shorter spectral-wavelength dyes tend to perform optimally when using ex vivo analysis methods.

Green FLIVO™ In Vivo Apoptosis Kit #980, 981 Red FLIVO™ In Vivo Apoptosis Kit #982, 983

Browse protocols and data on the product pages to learn more, and contact ICT to discuss how these tracers would benefit your research.

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FLIVO is a trademark of ImmunoChemistry Technologies, LLC.
DyLight
® is a trademark or Thermo Fisher Scientific, Inc. and its subsidiaries.