Mitochondrial Depolarization

Changes in mitochondrial membrane potential can lead to the initiation of cell death or have implications in cellular metabolism studies. MitoPT™ Assay Kits assess changes in mitochondrial membrane potential and detect mitochondrial depolarization.

Mitochondrial Permeability Assay Kit

  

Excitation

   

Emission

  

Catalog Number

   

Data 

MitoPT™ JC-1 Assay Kit
Dual green/red fluorescence

 

488 nm

  

527 and 590 nm

 

924 (100 tests)
911 (400 tests)

 

Jurkat cells stained with MitoPT™-JC1 potentiometric dye. Healthy cells fluoresce red, dying cells fluoresce green.

MitoPT™ TMRE Assay Kit
Red fluorescence

 

549 nm

 

574 nm

 

9102 (100 tests)
9103 (500 tests)

 

TMRE-staining reveals heathy cells with polarized mitochondria and dying cells with depolarized mitochondria.

MitoPT™ TMRM Assay Kit
Red fluorescence

 

548 nm

 

573 nm

 

9104 (100 tests)
9105 (500 tests)

 

TMRM-staining reveals heathy cells with polarized mitochondria and dying cells with depolarized mitochondria.

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