Read recent publications from researchers around the world for August 2022:
Xia, M;David, L;Teater, M;Gutierrez, J;Wang, X;Meydan, C;Lytle, A;Slack, GW;Scott, DW;Morin, RD;Onder, O;Elenitoba-Johnson, KSJ;Zamponi, N;Cerchietti, L;Lu, T;Philippar, U;Fontan, L;Wu, H;Melnick, AM. BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Cancer Discovery. 2022 August 5; doi: 10.1158/2159-8290.CD-21-1566. Full Article
Hoechst 33342 Fluorescent Nucleic Acid Stain
Ratto, E;Chowdhury, SR;Siefert, NS;Schneider, M;Wittmann, M;Helm, D;Palm, W. Direct control of lysosomal catabolic activity by mTORC1 through regulation of V-ATPase assembly. Nature communications. 2022 August 17; doi: 10.1038/s41467-022-32515-6. Article
Magic Red Cathepsin B Assay, Magic Red Cathepsin L Assay
Zhong, G;Long, H;Zhou, T;Liu, Y;Zhao, J;Han, J;Yang, X;Yu, Y;Chen, F;Shi, S. Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia. Biomaterials. 2022 August 8; doi: 10.1016/j.biomaterials.2022.121690. Full Text
MitoPT JC-1 Assay
Akter, E;Tasaki, Y;Mori, Y;Nakai, K;Hachiya, K;Lin, H;Konno, M;Kamasaki, T;Tanabe, K;Umeda, Y;Yamano, S;Fujita, Y;Kon, S. Non-degradable autophagic vacuoles are indispensable for cell competition. Cell reports. 2022 August 30; doi: 10.1016/j.celrep.2022.111292. Article
Magic Red Cathepsin B Assay
Fernandez, MA;Bah, F;Ma, L;Lee, Y;Schmidt, M;Welch, E;Morrow, EM;Young-Pearse, TL. Loss of endosomal exchanger NHE6 leads to pathological changes in tau in human neurons. Stem cell reports. 2022 August 17; doi: 10.1016/j.stemcr.2022.08.001. Full Report
Magic Red Cathepsin B Assay
Krętowski, R;Cechowska-Pasko, M. The Reduced Graphene Oxide (rGO) Induces Apoptosis, Autophagy and Cell Cycle Arrest in Breast Cancer Cells. International journal of molecular sciences. 2022 August 18; doi: 10.3390/ijms23169285. Full Abstract
FAM FLICA Caspase-9 Assay
Mitrović, A;Senjor, E;Jukić, M;Bolčina, L;Prunk, M;Proj, M;Nanut, M;Gobec, S;Kos, J. New inhibitors of cathepsin V impair tumor cell proliferation and elastin degradation and increase immune cell cytotoxicity. Computational and Structural Biotechnology Journal. 2022 August 28; doi: 10.1016/j.csbj.2022.08.046. Text
CFSE Fluorescent Cellular Stain
Buscetta, M;Cristaldi, M;Cimino, M;La Mensa, A;Dino, P;Bucchieri, F;Rappa, F;Amato, S;Aronica, TS;Pace, E;Bertani, A;Cipollina, C. Cigarette smoke promotes inflammasome-independent activation of caspase-1 and -4 leading to gasdermin D cleavage in human macrophages. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2022 September 1; doi: 10.1096/fj.202200837R. Research Article
Hoechst 33342 Fluorescent Nucleic Acid Stain
Ngwa, DN;Agrawal, A. Structurally Altered, Not Wild-Type, Pentameric C-Reactive Protein Inhibits Formation of Amyloid-β Fibrils. Journal of immunology (Baltimore, Md. : 1950). 2022 August 17; doi: 10.4049/jimmunol.2200148. Abstract
Costar 96-Well Black Polystyrene Plate
Kawashima, A;Kiriya, M;En, J;Tanigawa, K;Nakamura, Y;Fujiwara, Y;Luo, Y;Maruyama, K;Watanabe, S;Goto, M;Suzuki, K. Genome-wide screening identified SEC61A1 as an essential factor for mycolactone-dependent apoptosis in human premonocytic THP-1 cells. PLoS neglected tropical diseases. 2022 August 1; doi: 10.1371/journal.pntd.0010672. Article
FAM FLICA Caspase-3/7 Assay
He, L;Wei, T;Huang, Y;Zhang, X;Zhu, D;Liu, H;Wang, Z. miR-214-3p Deficiency Enhances Caspase-1-Dependent Pyroptosis of Microglia in White Matter Injury. Journal of Immunology Research. 2022 August 22; doi: 10.1155/2022/1642896. Full Article
FAM FLICA Caspase-1 Assay, FAM FLICA Caspase-3/7 Assay, FAM FLICA Caspase-6 Assay, FAM FLICA Caspase-8 Assay
Yin, H;Wu, M;Lu, Y;Wu, X;Yu, B;Chen, R;Lu, J;Tong, H. HMGB1-activatied NLRP3 inflammasome induces thrombocytopenia in heatstroke rat. PeerJ. 2022 August 4; doi: 10.7717/peerj.13799. Full Text
FAM FLICA Caspase-1 Assay
Yoshioka, H;Komura, S;Kuramitsu, N;Goto, A;Hasegawa, T;Amizuka, N;Ishimoto, T;Ozasa, R;Nakano, T;Imai, Y;Akiyama, H. Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. Journal of bone and mineral metabolism. 2022 August 10; doi: 10.1007/s00774-022-01354-2. Publication
MitoPT JC-1 Assay
Martino, E;Balestrieri, A;Anastasio, C;Maione, M;Mele, L;Cautela, D;Campanile, G;Balestrieri, ML;D'Onofrio, N. SIRT3 Modulates Endothelial Mitochondrial Redox State during Insulin Resistance. Antioxidants (Basel, Switzerland). 2022 August 19; doi: 10.3390/antiox11081611. Abstract
Pyroptosis/Caspase-1 Assay, Green
Su, M;Chen, C;Li, S;Li, M;Zeng, Z;Zhang, Y;Xia, L;Li, X;Zheng, D;Lin, Q;Fan, X;Wen, Y;Liu, Y;Chen, F;Luo, W;Bu, Y;Qin, J;Guo, M;Qiu, M;Sun, L;Liu, R;Wang, P;Hwa, J;Tang, WH. Gasdermin D-dependent platelet pyroptosis exacerbates NET formation and inflammation in severe sepsis. Nature cardiovascular research. 2022 August 4; doi: 10.1038/s44161-022-00108-7. Citation
Pyroptosis/Caspase-1 Assay, Green, FAM FLICA Caspase-3/7 Assay, FLICA 660 Caspase-3/7 Assay
Funakoshi, A;Honda, T;Ito, T;Tokura, Y. Cholecystokinin receptor antagonist suppresses melanoma growth by inducing apoptosis of tumor cells. JID Innovations. 2022 September 1; doi: 10.1016/j.xjidi.2022.100153. Abstract
MitoPT JC-1 Assay