Fluoro SSAO by Cell Technology
Non Radioactive. Can monitor multiple time points to follow kinetics. Monitors Enzymatic Activity. One-step, no wash assay. Adaptable for High Throughput format. Enzyme Positive Control included in Kit.
Fluoro SSAO by Cell Technology
SSAO’s functional role has been suggested to be involved in: apoptosis, atherogenesis, cell adhesion,
leucocyte trafficking, glucose transport and local production of hydrogen peroxide. Elevated levels of SSAO have been reported in congestive heart failure, diabetes mellitus, Alzheimer’s disease and various other inflammatory diseases. In addition, by products of SSAO deamination, such as formaldehyde and
methylglyoxal, have been proposed to be involved in pathogenesis of cancer, aging and atherosclerosis.
The Fluoro SSAO detection kit utilizes a non- fluorescent detection reagent to measure H2O2 released from the conversion of Benzylamine to Benzaldehyde via SSAO. Furthermore, H2O2 oxidizes the detection reagent in a 1:1 stoichiometry to produce a fluorescent product resorufin. This oxidation is catalyzed by Peroxidase.
Fluorescence plate reader
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