Glutathione Colorimetric Detection Kit

Glutathione, γ-L-glutamyl-L-cysteinyl-glycine or GSH, is the most abundant non-protein thiol in cells. GSH is involved in the regulation of a number of essential biochemical processes within the cell. Primarily recognized as a key intracellular source of reducing power for combating the toxic accumulation of free radical byproducts, GSH is also involved with detoxifying and removal of exo/endogenous toxins and alkylating agents. In its role as a cell signaling agent, GSH is involved in DNA synthesis and cell proliferation regulation. Due to the genetically conserved molecular processes by which cells die, intracellular levels of GSH can favor a cell death pathway via apoptosis (adequate intracellular GSH stores) or via necrosis or autophagy (depleted intracellular GSH stores). Detection of a drop in intracellular GSH concentration in an experimental cell population relative to a negative (healthy cell) control is often indicative of an apoptosis induction event. ICT’s Glutathione Colorimetric Detection Kit is designed to quantitatively measure GSH and GSSG in a variety of samples.

Glutathione and Oxidized Glutathione

Absorbance Plate Reader

Whole blood, serum, plasma, erythrocytes, urine, cell lysates, and tissue samples

2-8°C

Domestic: Overnight Delivery; International: Priority Shipping

United States