Interleukin-34 (IL-34) is a homodimeric cytokine recognized by colony-stimulating factor 1 receptor (CSF-1R). IL-34 is involved in the survival, proliferation, and differentiation of mononuclear phagocytes. Mouse IL-34 Recombinant Protein is purified interleukin-15 produced in yeast.
Interleukin-34 (IL-34) is a homodimeric cytokine identified by high throughput screening of human recombinant secreted factors. It contains no known conserved domains and has no sequence homology with other cytokines. IL-34 is recognized by colony-stimulating factor 1 receptor (CSF-1R). CSF-1R also binds CSF-1, also called macrophage colony-stimulating factor (M-CSF). Both IL-34 and CSF-1 are involved in the survival, proliferation, and differentiation of mononuclear phagocytes, including monocytes, macrophages, dendritic cells, Langerhans cells, microglia, and osteoclasts.
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NENLEIWTLT QDKECDLTGY LRGKLQYKNR LQYMKHYFPI NYRIAVPYEG VLRVANITRL QKAHVSEREL RYLWVLVSLN ATESVMDVLL EGHPSWKYLQ EVQTLLENVQ RSLMDVEIGP HVEAVLSLLS TPGLSLKLVR PKALLDNCFR VMELLYCSCC KQSPILKWQD CELPRLHPHS PGSLMQCTAT NVYPLSRQTP TSLPGSPSSS HGSLP (215)
Recombinant proteins produced in yeast
The Mouse IL-34 protein can be used in cell culture, as an IL-34 ELISA Standard, and as a Western Blot Control.